Lecture Note
University
Swansea UniversityCourse
PM134 | MicrobiologyPages
4
Academic year
2023
Sanjeev K Ganesh
Views
0
TCA cucle /Erch cycle Substrate fo tretccycle - Acetyl COA Melanandna Pynivate pinvan Acetul 10A Euroayout compute Soxidau Pro - Planna me, Parwauding complex Benyrne E1 -yunwan w enzyme thiamine purphasinated t. , (up METPD hychonga Suporic and this the E3 classe deny roupoul elehadrosen are INADU 7 3ATP / FADIS 2ATD FAD NAD CoA hydroxycri COASH nuce-scof Pynware mamm NAD' puruphori it (FAN (02 HETPP upon and NADUT n particals remover 3rd step demn sencre Dimonday consumer denydrupoy anyon for pynival - Acetyl coA NADH carbon) 1st rxn- condensation rxn (6 carbon) compound (4C) oxalocuetate citrate synthase cirrate (21) actylich cuonitase socitrate (NADH) condaction (soutian demonage 2- (5C) Suvingl COA Order Letoglutame denuar (GTP) CO2 comper
summyl wa suminate tumarate FADM, malate Aerobic responsing allion pynivate Aaly w/ know artar rudative Substrate level pherphonylal" Guycolysis - s ATP I alunor- 2pynware Pyruvate dehyanogener = INADU - 3ATP complix in the cycu; (calculate with steps) SNADN = 9 ATP 3191241 IFADM = 2ATP 1GTP = IATP 15 ATP 15x2 = 30ATP all Pynuate disubrogenan comper OR gillowys Oxedutive 2 - 2 NADU = 6ATP oxidative I GNADA = 18AIP pynivate Guidarin P 2FADM = UATP Substr are 2UTP = 2ATP TCA are 7 30 l transport ATP ELECTRON TRANSPORT CHAIN 1st provin which receives - NADU dehydegenax NADPH --transport coenymes - e-are produced camed proteins Termnal e- culeptor - O2
In membrane - camer protein O2 tho esmat protons pumped out of plasma membrane- Transform e transport + phorphonylation coupled Oxidation followed P.M. Pro byphosphonylaten mito- Eu ATPgenerald Mitochandria consists of a lot of enzymes. NADH FADH2 TCA Entry sites NADU for NADth NAD+ WFAD al coenzyme Q FADIZ cutochrome oxidare ubiqueone, liqued souble NADH dehydrigina only camer not bound to protein cyto- a ; b, C1, a, a3 c-small water soluble complex I 11 III V 1m II- entrypoint 4 (,111, IV ATP generatn Atpgeneration eletron NADU demycrogence (for NADR - HATP generation Summate " for FADM 17 2e revolves 2 protons phosphonylation ratio Ep/03
INADH NAME demorgance in - BID conupre e complexi-ATD I MT-AP 11th b IV ATP l cycon 2010 i www L cytica cywaz 202 FADE futti Sumat developma I co Q III V b L 2AT1 Are 09 P 9 ! L : a i 202 an OXIDATIVE PHOSINO pulnton Energy from e- transport is and to make ATP chemosmolic hypo conformati malchange hypo
Electron Transport Chain and TCA Cycle in Microbial Cell
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