Channels in nervous system

long asion covered by shawn cells - Myelinsheath - Bassiel for ion flow 1ms Inssaltatory conduction C nod es of sanvet shorrell. sheath length in oplimized (or else the signal diminishes) conduction velocity of myelinated axon 100 m/s. Brain (2cells 1:1) Never Cell Citial Cell more in more in CNS PNS (1:10) (10:1) (OD) (AC) (MG) (SC) oligodenduoctes Shwan Astrocytes. - cells. Starlike Microglia Tissue myelin sheath several appelance. If act as areservoir macrophage in tNs. shwancell to 1++, Na+, CI in brain form dedicated 100 to Ineuron ion for impolse myelin sheath transmission. around several (inPNS) Promot synapse cells formation Promoteblood brainhauiel formation

00 membrane MBP (Myelin basic Protein) multiple Scle rosis ACI Autoadibody SC membrane Po Guillicume bar syndrome AutoAb specialized tight juncti in endothelial cell Endolhdla cells make special layer Blood brain baries Prevents alcohol easicy closs. the bauies and enter brc entryof blood born neuro transmitters. & toxins in to brain 12 hooding of nevotrans miltas 1 2 H Ht ATP uncoaled vesicle 2 movement of 6 vosideto activezone recovery of syraptic vesicle via 4 a vesidedocting a endocytosis H+ PM 5 affort of exocytosis everynaptic cell carl cla 00 Syraptic cleft

myosing - Organelle transport Veside transport myoin I&II - moscles. Veside Vtype pump Vacoule H+ATPase Vaccoule - largest organelle inplant accumilate 2 metabolites storage compallment toxins ions(Nat,Kt,C Incamplents - Malatestarage water Vacoole memb - Vtype H+ ATPase PPi ATP powered powered. (plant.poceuss large no:of PPI) (1) Na+ unwanted element in plant ADAPI 2Pi Na+/H+ pumpin vacale ATP PP:- Ht HH C1- type of Vtype H+ ATPase -ve charge No3 (Plant Vacoule lomen) PH=3-6 ion transport Sucroe Na+ cart favourable since vacous - in adidas H+ H+ Ht

of non reactive transported in high CODE Acctyl Choline receptor (pentamenic) X2 B V 8 2 acelyl choline (ligand ) required to on the channe b/w x&r & & & S transport both Na+/kt but generate more Na+, bcs net movement of Kt in less since extraceellilar com of Nat invery high andintracellulus kt in very low. Na+ /k+ channel Na Kt small large Solvation shell. Kit Kt chann