Differential Distribution of Protein and Cell Rate Maintenance

DIFFERENTIAL DISTRIBUTION of PROTEINS AND CELL FATE MAINTENANCE STEM CELL Totipolent Pionaira Neoblast Develop entirely to an organism Pieuripotent Harmatopoetic stem cell Maintenance of Stan Cell fate 1 cell receive some PAR proteins and (1) Assymetric division maintain stancell fate, other cell STEMIL lack this protein, they differentiate STEM CELL COMMA LITTED Differentiate to specific cell type.

TAX 1000003 Assymetric OF cell division neuroblast Ganglion Mother cell Neuron Glief cell 2) Stemcell niche (SCM) maintain niche maintenance of contact with a cell keepthen in stem cell fate and the cells that have no contact develop not to their specific fate SCM signals tomainfaln stem callate Stem cell renewal Stem cell stein cells committed celltypeA Band differentiate onsignal Cell type B. received

Gumaiium in Deosophilla (oocyledevelopment Capcell niche of geinline stem cell Inna sheath cell niche of sumatic stemcells ( jotticle stemcell) niche provide signal (Hedgehig, wot etc) to maintain the stem cell fale. Intestinal Stemcell continouslyermoved 4-5day, invaginated highly basal portion (crypt) migration differentiatingcells. Differentcells Aprorptive enterocytes eyest 14 stemsell Enteroendocrine cell I LGR5 stemcal Toftcells cell Transcription Globlet cell from Paneth cell (niche) Bone manowstromal cell. - niche of harmalopoctic stemcells. 11.3 common the involved in developmentfall blood cells D. Eeythropoetin - Eryltrocyton G-CSF - Granulocyfes Thrombopoelin - Megakaujocytes M-CSF - Monocytes of GM-CSF - Eornophils xr 112,117 - T&B slymphocytes