Toxin Against Microfilaments

p {margin: 0; padding: 0;} Toxins which inhibit microfilamon Cytochalacis D-fungal alkaloid Binds to the + end and leads to depolymerization. by blocking to rther addition @ + end Latramcollin - actlike thymosin B-4 and make it Spongetoxin unavailable for Polymerization Phalloidin Amanita palloides Bind @ interface between subunits in f-actin and Pervent actin filament from polymeizing. Jasplakinslide - sponge toxin enchance actin polymarization by enchancing actin pay malization -uncontrolled polymelization Actin Organization Peoteins - organizing in different shapes & structures - Require Ca 2+ for function. 00 Surbrin - microvilli ,jilopodia, focal adhesion spaces od 00 L-actinin (spaceus) -stress fibas, filopodia, muscle Zline co- 00 PO 8 po- of Spectrin - tetrames Q2 B2 - RBC ,cellcorte B a 00 d B