Lipid Catabolism

LiPid Catabolism lipide microbial lipases Glycorol +fatty auids CH2OH CHOH ATP ADP 12 NAD NAIGH+H+ CH-OH 2 HO- CH Ho- CH. O Glyunol Kinase glycerd phosphat 1 (H,OH CH2- PO dehydrigin CH2-0- P glycerol glyund -3-P dihydrong autoned 3-oxdn pathway Fatty avids are activated before oxidation. All anzymes involved in the oxdn of fatty acids are present in the mitochondria Fathy Acids fathyacyl COA synthase /thiokinaic outer mitochandri fatty Ange WA membrane It is coupled with ATP hydrolysis to AMD and 2 pi]

- H is the regulatory step for the FA oxdn pathway. fatty Anyl WA. B Oxdn. Acetyl CoA. Citnc aud cycle. NADH, FADH2 and GTP. Utilisation of NADH and FADH2 in oxidative phosphorylatin generating ATP.) Respiratory 2H+ + 1/202 (e H2O ADP Pi ATP

B oxidation of fatty acyl-lon Palmitayl - w Acyl COA FAD dehydrogman FADH2 Encyl WA H2O enoyl- WA hydratae. & hydroxy -acyl COA NADt NADH+HIK B hydroxy acyl anyl WA clehydrogenoue B - Ketoacyl - -COA acyl COA COASH :- ! acetyltransferas Augu lon + Acetyl COA