Drug Structural Chart

Carbocation Carbanion Free Radical hybridisation sp2 sp sp2 of central C

Reactions 1. Combination with an 1. Displacement gives either stable products H anion + H3C-I (ter mination) or leads to Reacts with-rely charged EIQU CO2Et (III). other radicals leading to 13 species u + I eg H2(CH2 ith th EtO2C CH CO2EL propagation reactions M3C R.+R'. R-R' a 2. Addition to multiple bond addition of Griguard to 2CH3 in 13-CM3 +CH=CH2 = 2 Elimination of proton carbonyl group. I Abstraction of another atom unsaturated compound Donates proton to yield H =000 orgroup usually H+ Mo -H H + RMg- R.TR'H RHHR. H3C CH3 HCCC CH3 H3C CH omgx 2. Addition to multiple bond / I + R R. + CCC R CAL ab us 3. Elimination HK i- t 07 H2 OH H2CHC another double new racheal may as add to + Cth 2 vinyl phymerization Br Br H2C=Chl 3. Decomposition 3. Rearrangements Intermolecular alkylation 4. Combin ation with cation 4. Rearrangement by carbocation F FC NaOEE FL Hi OFU F F

DI Chb + 11 M3C- + CH oEt R second generated E reach F CF R YY with = species. leads to polymeni zation reaction 5- Rearrangements withing Base catalysed Conversion R H 4 y of ethers to secondary or3"alcond + + MyLHRLi SR CH CH M O-R' OR OH Ether RICH-R' 1,2 by dride shift. alcohol OH I H CH Stevens Quart. NY sells to H3C + 3 CH2 H3 it Cuz animes using strong base Allytic H Rearrangements th Q R Base 11 N 1 H3C + HC 41] R H R u OEt I Arch CUFR CH H3C the ELOH H3C-C R' CH + H -R' H th R "R" R H3C R' H OEt