DIFFERENTIAL DIAGNOSIS 1.3. Organic causes Certain organic pathologies can lead to confusion with depression such as: Neoplasia, Parkinson's disease, brain tumors, requiring the practice of additional explorations Hypothyroidism should be looked for in particular bradycardia, chilliness or increased weight. Addisson's disease which is characterized by intense psychological and physical asthenia with abulia. Diabetes or asthenia is common. It should be noted that organic pathology should be sought in the absence of a triggering factor, in the absence of a personal or family mood history, in the presence of symptoms suggestive of an organic pathology or confusing elements or when the slowdown, the Asthenia or anorexia are clear without real depression of mood. 1.4. Mourning Although it can be complicated by a depressive state, mourning is distinguished by: ● Depressive ruminations remain centered on the lost being with painful feelings of injustice, revolt or anger ● The absence of psychomotor slowing and suicidal ideation ● Sensitivity to reassurance and reduction of symptoms over time 1.5. Anxiety disorders Depressive and anxiety symptoms are often intertwined, with one complicating the other. In favor of an anxiety disorder: ● The evolution of attacks of anxiety, whereas in depression, it is more or less permanent and typically predominantly morning ● The presence of other symptoms of the phobic or obsessive series ● Avoidance or reassurance behaviors and rituals 1.6. Psychotic disorders The acute delirious burst (BDA) poses a problem of differential diagnosis with delusional depression. In favor of BDA: the brutal beginning of a rich and polymorphous delirium, experienced intensely in an atmosphere of strangeness and anguish.
Schizophrenia ● Early form of schizophrenia with atypical depression ● Depressive states occurring during the illness ● Certain forms of schizophrenia: catatonic schizophrenia (state of stupor) and hebephrenia (deficit or negative signs). Delusional disorder 1.7. Madness The intellectual disturbances which accompany certain depressive states, especially in the elderly, often pose a differential diagnosis with a dementia process. A history of depression and the presence of instinctive disorders are in favor of depression. The therapeutic test allowsoften to distinguish between these two diagnoses (put on antidepressants) 1.8. Differential diagnoses of depression in children and adolescents - Attention deficit hyperactivity disorder, especially in school-aged children - Anxiety disorders - Conduct disorders - Variations of normal: any child or adolescent can experience depressive moments during their development that are not pathological. These variations from normal are differentiated from an authentic depressive episode by their transient nature and the low impact on the child's life.