nifedepine -gen - Calcium channel blocker (Adulat Procardia XL) trade dose: PO (ER) 30-60mg QD Therapeutic class : Drug for HTN and angina max ( 120mg/day) ace - nifedipine Pharmacological Class: Calcium channel blocker actions/uses: prescribed for HTN and van ant vasospastic anging. - sometimes for Raynand's 1 henemenom which the SPIS shall arienes cause episodes of reduced blood flow to end - blocks calcium channels in myocardial and vascular smooth musde + eridles affects Ingers cardiac those in cornary artenes = coronary dilation, & 02 usage by / CO output and in BIP caps - available as IR and ER tabs. (IR CAIS/IRTABS) - IR 0 approved for HTN * only ER for HNV do 0 admin IR tabs if impending MI is suspected or within 2 weeks following a confirmed MI. - administer whole- 0 crush!* if chewed/crushed/dinned, whole dose will be delivered atonce.) Preg cat: C CCC ale constipation onset: 30 Omins cancauseconstration* peak: 6hrs Duration 24hrs a/c: usually minor and ilt vasodilation HA, diziness, peripheral edema, heartbum, nausea, flushing. To avoid rebound HMN, d/c gradually, all at once.
rare: can cause paradoxical in ongina pain rlt hypotension or HF CCB)R/t & contraindications prior hypersensitvityallogy to nifedipine or other CCBS. Interactions - use Drug: T additive Betablocker effects = on b/p if taken (Blockers' T other together HTN meds. - -0 good!!!) can digoxin 13 bradycardia and digoxin toxicity 101/1) - T statins alcohol potentiates vasodilating action of nifedepine and could lead to syncope caused by in Blp. (alcohol B/P always LABS 1 alkaine phosphatase, lactase dehy drogenase, ) ACT, CPK, AST. Herball Food Grapefruit juice can enhance absorption can Bly HR melatonin Sleep 222 (ccc) interacts t(CCC) (222) Txfor overdose: tx T vasopressors most common S/S hypotension. t possible CA infusions. remember H relates back tangma