Metoprolol

metoprolol - gen blockers Beta1 Adrenergic Blocker 101's are beta (lopressor Tropol XT - trade dose: POLER) 50-100mg BID QD or Therapeutic class Dmg for HP I HIN MAX 400mg/ day Phannacological class: Betal Adrenemic blocker actions uses: available in tab sustained release tab IV Reg. release approved to tx HF. - T doses affect Beta 2 receptors in bronchial SMOOTH muscle reduces sympathetic stimulation of the I & cardiac workload. - slows progress of HF I reduces long term effects - combined T ACEI I ARBS to tx HF. TX angina I HIN, reducing cardiac 00mg lications s/p ml. agminalerts: - monitor EKG ,BP, HR - dunng IV admin) - check HR BP before 10 ad min Holf if IIR

a/e: minor and r It autonamic activity. Beta Blocker Slow HR and hyporension. -monitor pts t HF b/c of itselfeetson I Brady cardia - abnormal sexual function ,drowzy, fatigue, insomnia contraindications pts T cardiogenic shock sinus bradycardia, (impoience He ibido) Heart block 71st degree, Hypoten sion, overt cardiac failure -caution M pts T asthma and hx of bronchospasm b/c drug can affect beta2 receptors if taken at high doses interactions: drug use T digoxin bradeycard 19 (blcalsolones use T HIN I ACE) (ARBS) additive hypotension Blp can enhance insulln I PO diabetic drugs & BIS use T verapamil r/o heart block and labs: uric acid,linds, bradycardia k+ ,bilirubin, alk. phosphatas, creat, and ANA Herbal/Food Hawthorn actions LB/P TX of overclose Atropine or isoproterenol can be used to reverse bradycardia caused by overdose B/P can bereverside vasopres sur (doramine/dobutaming