Fatty Acid Beta-Oxidation Overview

B-oxidation of fatty Acids Difinition Site Steps Regulation Impaired Energy Gain xidation MituCandria at B.Car ben Activation Liver Transport B-oxidation & In cytoplasm Heapt AcetyLCoA Fatty Acid SKM Not Agl CA synthetose "Next Pages" Enzyme Brain Acl(gl CoA By Alzaeem

STePS Acti Transport B-oxidation AcylGA Outer Membrane: CoA Dehydrogenase ACyLCoA CPTI AcyL Carnitine A 2 Trans enoyl CoA + FADH2 A2 Trans Cart Hydratase Inner Memberate ACLL Carnitine In B- Hydroxy Acyl CAA out CAT Carnitine B.Hydrang AglGA Dettydrogenase B-Keto ACgl GA +NADH+H Acyl Corporative CPT II AcyLGA Thirolase Acyl CoA Acetyl CoA

Impaired Energy Gain Number of cycles = Carbon AToms - I Carnitire Causes 2 Hemodialysis - liver Disease Number of Acetyl GA= Carbon AToms Malnutration 2 STarrati Vegeterians odd Number C.PTI Affect Liver fatty Acid oxidation CPPT II Affects SKM ProPiony / CoA Acetyl CA Camitine Sources Dietary (Meat) Energy Gain Law Endogenous from SuCCiny LCoA 1.+ (1- XIV Methionine Lysina Regulation vitamin B12 MethylMalonyl Co. Increase Inhibit Diabetes STar Vation feeding Neurological Manifestations Insulin Mellitus CarboHydrates